[HTML][HTML] Recent advances in mass spectrometry based clinical proteomics: applications to cancer research
A Macklin, S Khan, T Kislinger - Clinical proteomics, 2020 - Springer
… focus on the discovery of clinically-relevant biomarkers, there … and PgR are used to classify
breast cancer subtypes which has … sample preparation in clinical studies have been shown in …
breast cancer subtypes which has … sample preparation in clinical studies have been shown in …
[HTML][HTML] Mass spectrometry-assisted gel-based proteomics in cancer biomarker discovery: approaches and application
R Huang, Z Chen, L He, N He, Z Xi, Z Li, Y Deng… - Theranostics, 2017 - ncbi.nlm.nih.gov
… Furthermore, the challenges in validation of MS biomarkers … demonstrated that the
biomarker candidate they discovered … as a potential source for breast cancer biomarkers 183 . …
biomarker candidate they discovered … as a potential source for breast cancer biomarkers 183 . …
Clinical potential of mass spectrometry-based proteogenomics
… of cancer biology and biomarker and drug target discovery in … from two PDX models of breast
cancer demonstrate that only … and proteogenomic biomarker discovery to clinical validation, …
cancer demonstrate that only … and proteogenomic biomarker discovery to clinical validation, …
[HTML][HTML] Identification of novel alternative splicing biomarkers for breast cancer with LC/MS/MS and RNA-Seq
… to discover novel alternative splicing biomarkers from the … and 90% of them were confirmed
as the predicted AS events by … and 40 breast cancer plasma samples, we demonstrated that …
as the predicted AS events by … and 40 breast cancer plasma samples, we demonstrated that …
[HTML][HTML] Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine
Y Hu, Z Wang, L Liu, J Zhu, D Zhang, M Xu… - Chemical …, 2021 - pubs.rsc.org
… Another study demonstrated that quantitative biomarker … supposedly homogeneous group
of breast cancer patients, allowing for … It was confirmed that the classification of breast cancer …
of breast cancer patients, allowing for … It was confirmed that the classification of breast cancer …
Mass spectrometry based translational proteomics for biomarker discovery and application in colorectal cancer
H Ma, G Chen, M Guo - PROTEOMICS–Clinical Applications, 2016 - Wiley Online Library
… used to isolate CSCs in breast cancer 105. Regardless of their stemless … many candidate
biomarkers do not get beyond a proof of … Many candidate protein biomarkers of proven clinical …
biomarkers do not get beyond a proof of … Many candidate protein biomarkers of proven clinical …
[HTML][HTML] An integrated quantitative proteomics workflow for cancer biomarker discovery and validation in plasma
… in various cancers, while we have demonstrated here a … in instrumentation and mass
spectrometry-based platforms have … of plasma from patients with breast cancer: stage-specific …
spectrometry-based platforms have … of plasma from patients with breast cancer: stage-specific …
[HTML][HTML] Data-independent acquisition mass spectrometry (DIA-MS) for proteomic applications in oncology
… acquisition as a rapid proteomic pipeline for the analysis of … 1078 breast cancer patients
respectively, which confirmed the … DIA-MS has shown some success in biomarker discovery is in …
respectively, which confirmed the … DIA-MS has shown some success in biomarker discovery is in …
Mass spectrometry-based draft of the mouse proteome
… Our analysis confirmed expression of 13,538 genes with previous … We and others have
previously shown that the proteomic … of interesting molecular pharmacodynamics biomarkers. For …
previously shown that the proteomic … of interesting molecular pharmacodynamics biomarkers. For …
Internal standard triggered-parallel reaction monitoring mass spectrometry enables multiplexed quantification of candidate biomarkers in plasma
JJ Kennedy, JR Whiteaker, RG Ivey, A Burian… - Analytical …, 2022 - ACS Publications
… Previously, mass spectrometry-based approaches have been … list of 1314 candidate breast
cancer biomarkers. Since these … We demonstrate that IS-PRM can be deployed on plasma …
cancer biomarkers. Since these … We demonstrate that IS-PRM can be deployed on plasma …